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KMID : 1009020140120030218
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Clinical Psychopharmacology and Neuroscience
2014 Volume.12 No. 3 p.218 ~ p.221
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Two-channel Near-infrared Spectroscopic Analysis of Association of Paranoia Symptoms with Prefrontal Activation
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Kazuki Hirao
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Abstract
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Objective : The relationship between paranoia symptoms and underlying prefrontal cortex mechanisms among healthy subjects was analyzed using near-infrared spectroscopy.
Methods : Seventy-eight healthy subjects were assessed for paranoia symptoms using the Japanese version of the Paranoia Checklist. Changes in hemoglobin concentrations were assessed using 2-channel near-infrared spectroscopy on the surface of the prefrontal cortex while subjects performed a verbal fluency test.
Results : Changes in the concentration of oxygenated hemoglobin in the prefrontal cortex during a verbal fluency test did not correlate with the Japanese version of the Paranoia Checklist.
Conclusion : Our findings show that the symptoms of paranoia do not negatively affect the prefrontal cortex function among healthy subjects.
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KEYWORD
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Paranoia disorders, Prefrontal cortex, Near-infrared spectroscopy
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